منابع مشابه
Extracellular Vesicles in Regenerative Medicine, a Brief Review
Extracellular vesicles were initially known as cellular waste carriers, while recent studies demonstrate that extracellular vesicles play important biological roles in all aspects of life-from single cells to mammalians. Their pathophysiological roles in some diseases like cancer are being decoded. Extracellular vesicles are divided into some classes and there are different strategies to isolat...
متن کاملExtracellular Vesicles – Powerful Markers of Cancer EVolution
Solid tumors are likely derived from the coevolution of neoplastic cells, stromal components, vasculature, and immune cells (1). As tumors evolve and progress, an array of molecular changes accumulate giving rise to multiple cell subpopulations, each with the ability to divide and mutate further. In addition, neoplastic cell populations are able to modulate the behavior of other types of cells ...
متن کاملSignaling by Extracellular Vesicles Advances Cancer Hallmarks.
Mammalian cells secrete various extracellular vesicles (EVs; exosomes, microvesicles, and apoptotic bodies) that differ in biogenesis, composition, and function. Each vesicle type can originate from normal or cancerous cells, transfer molecular cargo to both neighboring and distant cells, and modulate cellular behaviors involved in eubiology and pathology, such as tumor development. Here, we re...
متن کاملDistinct Small RNA Signatures in Extracellular Vesicles Derived from Breast Cancer Cell Lines
Breast cancer is a heterogeneous disease, and different subtypes of breast cancer show distinct cellular morphology, gene expression, metabolism, motility, proliferation, and metastatic potential. Understanding the molecular features responsible for this heterogeneity is important for correct diagnosis and better treatment strategies. Extracellular vesicles (EVs) and their associated molecules ...
متن کاملEXTRACELLULAR VESICLES AND THEIR THERAPEUTIC APPLICATIONS: A REVIEW
Background & Aims: Extracellular vesicles are double phospholipid layer vesicles releasing from several cells. These particles contain bio-molecules including mRNA, miRNA, DNA, proteins, and lipids which play a pivotal role in the cell to cell communication. Once delivered, they participate to change target cell function, fate, morphology, differentiation, and growth. The present study is a re...
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ژورنال
عنوان ژورنال: Bioactive Materials
سال: 2021
ISSN: 2452-199X
DOI: 10.1016/j.bioactmat.2021.03.015